PROHLÍŽENÍ ABSTRAKTA

WHAT WE CAN LEARN FROM MODELING CARDIAC FUNCTION?
Tématický okruh: Varia
Typ: Ústní sdělení - lékařské , Číslo v programu: 492

Platzer D.1, Zorn-Pauly K.2

1 Department of Biophysics, Center for Physiological Medicine, Medical University Graz, Austria, Graz, Austria, 2 Center for Physiological Medicine, Medical University Graz, Graz, Austria


The system approach considers control of cardiac function as interaction of different cardiovascular components. Mathematical and computational modeling aims to bridge the gap between experimentally gained observations of isolated components and the desired understanding of the whole living organism in health and disease. This approach requires a clear definition of the purpose, the assumptions, and the boundaries of the model. It is necessary that mathematical models have to be based on reliable experimental data. We witness an amazing development and refinement of biophysical methods to quantitatively describe biological phenomena with increasing accuracy. In parallel, sophisticated computational techniques enable the increasingly efficient solution of ordinary and partial differential equations, which are used to describe these systems in the language of mathematics.